Diverse RNA granules have been intensely researched. Yet, fundamental questions remain unaddressed:

  1. Which mRNAs enrich in RNA granules?
  2. How do mRNAs become enriched in RNA granules?
  3. How do mRNAs influence granule assembly?
  4. What happens to the mRNAs once they arrive in RNA granules?
  5. How are mRNAs regulated in RNA granules?
  6. How do granule-enriched mRNAs shape the biology of a cell?
  7. How do granule mRNAs become miss-regulated to drive disease?